Bicyclo[3.3.1]nonanes as synthetic intermediates. IV. Behavior of bicyclo[3.n.1]alkan-3-ones toward the Baeyer-Villiger oxidation.

Baeyer–Villiger oxidation of norbornan-7-ones: long-range substituent effects on regioselectivity

Baeyer–Villiger (BV) oxidation is a commonly employed reaction for the transformation of ketones into esters/lactones by organic peroxy acids or hydrogen peroxide. The BV reaction is extensively used since when it is suitably juxtaposed in a synthetic sequence, it can lead to the shortening of carbon chains, amplification of functionality in carbocyclic rings and chains, and transformation of c...

The Baeyer-Villiger reaction: new developments toward greener procedures.

An aerobic, organocatalytic, and chemoselective method for Baeyer-Villiger oxidation.

Crystal structure of a Baeyer-Villiger monooxygenase.

Flavin-containing Baeyer-Villiger monooxygenases employ NADPH and molecular oxygen to catalyze the insertion of an oxygen atom into a carbon-carbon bond of a carbonylic substrate. These enzymes can potentially be exploited in a variety of biocatalytic applications given the wide use of Baeyer-Villiger reactions in synthetic organic chemistry. The catalytic activity of these enzymes involves the...

Conversion of Furans by Baeyer-Villiger Monooxygenases

Various furans are considered as valuable platform chemicals as they can be derived from plant biomass. Yet, for their exploitation, follow-up chemistry is required. Here we demonstrate that Baeyer-Villiger monooxygenases (BVMOs) can be used as biocatalysts for the selective oxidation of several furans, including 5-(hydroxymethyl) furfural (HMF) and furfural. A total of 15 different BVMOs were ...